I read the book Frostbite this year, which is the best book I've read in a few decades, think Fast Food Nation but for refrigeration. The final chapter was about the global seed vault and the authors visit to tour--the tour was closed down because of water leaking in due to permafrost melt--which hadn't happened before and had caused electrical and issues with the refilrigeration keeping the seed vault correctly temperatures and ventilated.
Even the grandest schemes won't matter against the chaos ahead if we don't drastically change.