WormFood

alphafold had set the field of protein folding back a decade

I love retro gaming on real hardware, but the prices for turn-of-the-millenium software are outrageous. whatever was popular 20 years ago tends to suddenly become very expensive, but after a certain point the price does go down again. I used to collect NES games, when they got too expensive I moved to big box pc games, and now I'm building a Wii and Atari 2600 collection. The 2600 is so old that most of the people who are nostalgic for it aren't actively collecting it. meanwhile, the Wii is still comparatively new (though that will likely change in a few years).

so, I guess my advice is: buy whatever's cheap. I had never played the 2600 before but I ended up developing a genuine appreciation for the console. similarly, I'm picking up Wii games because I love the Wii and I want to make sure I have all the essentials before they get really expensive.

Another alternative is to just buy a console and then use a flashcart/softmod. or use an FPGA system, which will get you a native-like experience.

it sucks that a thing I like so much has become a festival of unrestricted capitalism, but I think it's still possible to carve out a niche and enjoy yourself.

I'm probably not going to pay $10 a year with additional fees to have my music on a website unless a lot of people are already using it

this pretty much sums it up. I thought trump would be incoherent, but some of the stuff out of his mouth was borderline surreal. Harris had completely tuned herself to 'beat' trump, and while it worked, it's painfully clear that she doesn't have a single original thought - nothing but platitudes, the same canned phrases about working families and small businesses, same tired defence of Israel.

you can still get the logical journey of the zoombinis on steam (and on android/ios). no joke, I think that game taught me deductive reasoning

I have spent the last 10 years of my career writing open source scientific software

ignorance is one thing, but it's a whole nother level of loser behaviour to intentionally do unpaid work for big tech companies in your free time

this is fine until you need autotools which is worse than cmake

I understand that this is a big loss for the emulation community, but as someone who did a bit of romhacking during COVID, I found their moderation to be terrible and arbitrary.

it's still mostly red hat even for arm, though Cray (who still supply a lot of machines here in the UK) ship a horribly butchered version of SLES

typeset my thesis using latex, biber and zotero. Very painless, the only slightly painful part was configuring the character encoding

irrelevant to the thread, but it actually took only 3 years for clement atlee's government to create the UK's national health service