I have recently installed AetherSX2 on my stock Pixel 6 and tried 4 games:
- Tony Hawk Undergroud 2 - works perfectly fine
- Tony Hawk Underground - same as above
- LOTR: Return of the King - small FPS dips (marginal) but some menu text missing
- Prince of Persia: Sands of Time - no happening, terrible FPS
But I haven't played around with any settings yet, I'm using the default Safe settings. If you want, I could run some tests. But I'm absolutely clueless with this stuff, never done it before.