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FDA says decongestant in many cold medicines doesn't work. So what does? (apnews.com)

submitted 3 days ago* (last edited 2 days ago) by MicroWave@lemmy.world to c/health@lemmy.world

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Summary

The FDA has proposed phasing out oral phenylephrine, a common decongestant in cold medicines like Sudafed PE and DayQuil, after studies showed it is no more effective than a placebo.

The drug, ineffective when swallowed due to breakdown in the stomach, remains usable in nasal sprays.

Alternatives include pseudoephedrine, nasal sprays, and steroid treatments like Flonase.

The regulatory process to remove phenylephrine could take over a year, but experts argue removing ineffective options will help consumers choose better remedies for congestion. Drugmakers are expected to challenge the proposal.

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[–] Rivalarrival@lemmy.today 2 points 2 days ago

Oxymetazoline reduces congestion in seconds, but causes terrible rebound congestion.

Phenylephrine doesn't work when taken orally, but it is extremely effective nasally, with far less rebound congestion than oxymetazoline nasal sprays.