The human fatality rate of COVID-19 is 1-3%, depending on how you count cases. From what I've seen reported, the human fatality rate of this strain of bird flu is closer to 50%.

(Lots of "ifs" coming) If this starts to spread human-to-human, if it spreads as easily as COVID, and if we don't lock down and this becomes endemic like COVID, COVID will look like a walk in the park compared to what this will do. I'm crossing my fingers that COVID was in that mortality sweet spot where it was bad enough to cause a lot of deaths but not quite bad enough to make officials make people angry with actually taking care of the problem. 50% mortality should be comfortably on the side of "deal with it at all cost."