I was involved with an Indie game that was priced at roughly $15. It literally sold for 10 cents in those regions with Steam's recommended pricing, mainly due to the accelerating inflation, and within hours of release, 20% of the sales came from these regions because of people abusing VPN. The pricing was quickly adjusted before that percentage could grow any larger.

When people can just get a freshly released game at a 99.5% discount, you might as well not sell the game at all in those regions.