this post was submitted on 16 Sep 2023
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Researchers from Pritzker Molecular Engineering, under the guidance of Prof. Jeffrey Hubbell, demonstrated that their compound can eliminate the autoimmune response linked to multiple sclerosis. Researchers at the University of Chicago's Pritzker School of Molecular Engineering (PME) have developed

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[–] evatronic@lemm.ee 14 points 1 year ago (1 children)

mRNA vaccines had been in development for about 20 years prior to 2019. We were lucky.

[–] PeleSpirit@lemmy.world 5 points 1 year ago (1 children)

How long has this been in development?

[–] evatronic@lemm.ee 9 points 1 year ago (1 children)

It's difficult to pin down "when did mRNA research begin?" but, a pretty good date is to say, "The 1990s." But you could go back as far as 1960 or 1970 if you were being technical.

https://publichealth.jhu.edu/2021/the-long-history-of-mrna-vaccines has a good write-up.

mRNA technology is a HUGE breakthrough. Like I said, we were lucky it was essentially ready and able to help with the COVID vaccine development when it was.

[–] PeleSpirit@lemmy.world 2 points 1 year ago (1 children)

Wait, are inverse vaccines the same as mRNA? That's what I was wondering about. Have the inverse vaccines been on the research agenda for awhile? As I said before, I'm hoping the mRNA breakthroughs help the reverse vaccines go quicker.

[–] kbotc@lemmy.world 5 points 1 year ago

Nope. In this case they figured out that you can “tag” molecules with N-acetylgalactosamine, and that convinces the Liver to tolerate the molecule that causes the immune reaction and signal the immune system. My wife has a major anaphylactic reaction to certain shrimp and this would be a game changer.