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this post was submitted on 14 Apr 2024
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Damn here's another "joke" about contraceptives and bone fractures
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD009849.pub3/full
And one another abput yellow fever and HIV
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD010929.pub2/full
And influenza vaccines in cancer patients
https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008983.pub3/full
And there's another 96 on the first search tab alone!
Just what are those clowns at the Cochrane Library up to eh?
Relevance?
They all use the same Newcastle-Ottawa system to score studies based on their likelihood of bias in the exact same way the Cass reviews do. The method you described as a joke.
It's not an indicator of bias, no causal study has been done to show that there is a relationship between bias and the Newcastle Ottawa scale
Studies that self select their cohort and don't include adequate controls are more susceptible to bias than those that do otherwise. Evaluating studies based on their susceptibility to bias is a vital part of the systematic review process.
You can read more about it here https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp
But not actually proof of bias.
Ah young padawan, there is no such thing as proof of bias. There is merely the risk of susceptibility of it.
Exactly which is why the Ottawa whatever standard is not sufficient to discard a study. You have to do more.
Again, you really need to feed this startling discovery back to the medical community which has been using NOS for over 20 years. What a scandal.
No the medical community largely respects the short comings and uses of the Ottawa protocol. That's what made Class's report so insulting.
Blimey, you're speaking for the medical community itself as a whole now, pray tell then why haven't they binned every systematic review ever carried out using the NOS system?
Why after 20 years of use is this system only being rubbished after two reviews into gender affirming healthcare in the UK were published?
Why are you the only person complaining about the Newcastle-Ottawa system when everyone else online is making up lies like "98% of data was dismissed"?